Discussion on key points of air conditioning system design for a high-biocontainment production plant

Combined with an actual project case, this paper presents the air conditioning system division principle, ventilation form, indoor air distribution, pressure control as well as the design key points and countermeasures of some biosafety key protective equipment related to the ventilation system in the high-biocontainment production plant. The design of the air conditioning system in the high-biocontainment production plant should be based on the risk assessment to determine the biosafety protection zone boundary, the division principle of the air conditioning system and the parameters of the biosafety key protective equipment. The practice shows that the valve setting mode of constant supply air volume and variable exhaust air volume can realize the stable operation of the air conditioning system, and can also meet the ordered pressure gradient in the conversion process of different working conditions.